PAVURUTAMAB

UNII:	GLR3JG8TZU
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	PAVURUTAMAB
GSRS Full Record:	GLR3JG8TZU i

2250292-39-6
AMG-701
AMG701
ANTI-BCMA X ANTI-CD3 BITE (BISPECIFIC T CELL ENGAGER) ANTIBODY CONSTRUCT
ANTI-BCMA X ANTI-CD3 BITE AMG 701
ANTI-BCMA/CD3 BITE ANTIBODY AMG 701
BCMA/CD3-DIRECTED BISPECIFIC T-CELL ENGAGER ANTIBODY AMG 701
IMMUNOGLOBULIN SCFV-SCFV-SCFC, ANTI-(HOMO SAPIENS TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 17 (B-CELL MATURATION PROTEIN, CD269_ANTIGEN)) TNR17 AND ANTI-(HOMO SAPIENS T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN (T-CELL SURFACE ANTIGEN T3/LEU-4 EPSILON CHAIN, CD3E_ANTIGEN)) CD3E; MONOCLONAL ANTIBODY SINGLE CHAIN; BISPECIFIC; VARIABLE CHAINS (1-502); ANTITNR17 (1-249): (HOMO SAPIENS VH (IGHV1-46*01 (G49>C(44)) (85%) (IGHD)-IGHJ4*01 (93%)) (8.8.14) (1-121)-TRIS(TETRAGLYCYLSERYL) LINKER (122- 136), (HOMO SAPIENS V-KAPPA (IGKV1-33*01 (92%) IGKJ1*01 (Q120>C(236)) (92%)) (6.3.9) (137-243),-SERYLTETRAGLYCYLSERYL LINKER (244- 249); ANTI-CD3E (250-502): (VH (MUS MUSCULUS IGHV10-1*02 (92%)(IGHD)- IGHJ3*01 (87%)/HOMO SAPIENS IGHV3-73*01 (87%)-(IGHD)-IGHJ5*01)) (8.10.16) (250-374)-TRIS(TETRAGLYCYLSERYL) LINKER (375-389) V-LAMBDA (HOMO SAPIENS IGLV7-43*01 (85%) IGLJ3*02) (9.3.9) (390-498),-(TETRAGLYCYL) LINKER (499-502) CONSTANT CHAINS (503-986), HOMO SAPIENS IGHG1*03 (CH1 DEL, (HINGE 6-15 (503-512)), (CH2 R62>C(574), N67>G(579), V72>C(584)) (503-729) -HEXAKIS(TETRAGLYCYLSERYL) LINKER (730-759) HOMO SAPIENS IGHG1*03 (CH1 DEL, (HINGE 6-15 (760-769)), (CH2 R62>C(831), N67>G(836), V72>C(841)) (760- 986)), NON-GLYCOSYLATED, PRODUCED IN CHO CELL.
IMMUNOGLOBULIN, ANTI-(HUMAN TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY PROTEIN TNFRSF17) (HUMAN MONOCLONAL BRA-HWZV 1 SINGLE-CHAIN VARIABLE FRAGMENT VH1-(GGGGS)3-VL1) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN CD3 ANTIGEN .EPSILON.-CHAIN) (HUMAN MONOCLONAL BRA-HWZV 1 SINGLE-CHAIN VARIABLE FRAGMENT VH2-(GGGGS)3-VL2) FUSION PROTEIN WITH FUSION PROTEIN WITH PEPTIDE LINKER (GGGG) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN .GAMMA.1-CHAIN C-REGION C-TERMINAL FRAGMENT) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS)6 FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN .GAMMA.1-CHAIN C-REGION C-TERMINAL FRAGMENT)
PAVURUTAMAB [USAN]
Pavurutamab [WHO-DD]
pavurutamab [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

PAVURUTAMAB

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