FDA's Global Substance Registration System

FDA's Global Substance Registration System enables efficient and accurate exchange of information on substances through their Unique Ingredient Identifiers (UNIIs) which can be generated at any time in the regulatory life cycle.

Learn how to search

Read about how GSRS search works and find substances based on partial text.

Download substance data

Download lists of UNIIs, names, codes, and attributes for substances registered in GSRS.

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.