GREZIPRUBART

UNII:	ZQL8925JUB
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	GREZIPRUBART
GSRS Full Record:	ZQL8925JUB i

2894136-80-0
Greziprubart
H-gamma1 heavy chain Homo sapiens (1-449) [VH (Homo sapiens IGHV3-72*01 (88.8%) -(IGHD) -IGHJ5*01 (91.7%) T122>V (113), CDR-IMGT [8.10.10] (26-33.51-60.99-108)) (1-119) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14, G1v14 CH2 A1.3, A1.2 (CH1 R120>K (216) (120-217), hinge 1-15 (218-232), CH2 L1.3>A (236), L1.2>A (237) (233-342), CH3 E12 (358), M14 (360) (343-447), CHS (448-449)) (120-449)], (222-219')-disulfide with L-kappa light chain Homo sapiens (1'-219') [V-KAPPA (Homo sapiens IGKV2-28*01 (89.0%) -IGKJ2*01 (100%), CDR-IMGT [11.3.9] (27'-37'.55'-57'.94'-102')) (1'-112') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (158'), V101 (196')) (113'-219')]; dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
Immunoglobulin G1 [236-alanine,237-alanine], anti-(human complement C5a) (human monoclonal STSA-1002 γ1-chain), disulfide with human monoclonal STSA-1002 κ-chain, dimer
STSA-1002
greziprubart [INN]
immunoglobulin G1-kappa, anti-[Homo sapiens C5 (complement 5) anaphylatoxin (C5a, C5 Pr678-751)], Homo sapiens monoclonal antibody

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

GREZIPRUBART

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