LUVAGROBART

UNII:	YEH533V6Y3
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	LUVAGROBART
GSRS Full Record:	YEH533V6Y3 i

2768355-18-4
AK-115
AK115
Gamma1 heavy chain humanized (1-451) [VH (Homo sapiens IGHV4-38-2*02 (80.6%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.7.15] (26-33.51-57.96-110)) (1-121) -Homo sapiens IGHG1*01 (100%), G1m17,1, CH1 K120, CH3 D12, L14, G1v14 CH2 A1.3, A1.2 (CH1 K120 (218) (122-219),hinge 1-15 (220-234), CH2 L1.3>A (238), L1.2>A (239)(235-344), CH3 D12(360), L14 (362) (345-449), CHS (450-451)) (122-451)], (224-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-39*01 (86.3%) -IGKJ2*02 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3, A45.1 (153), V101 (191) (108'-214')]; dimer (230-230'':233-233'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
Immunoglobulin G1 [238-alanine,239-alanine],anti-(human β-nerve growth factor) (human monoclonal AK115 γ1-chain), disulfide with human monoclonal AK115 κ-chain, dimer
Immunoglobulin G1-kappa, anti-[Homo sapiens NGF (nerve growth factor, NGFB, nerve growth factor beta polypeptide)], humanized monoclonal antibody
Luvagrobart
Luvagrobart [WHO-DD]
luvagrobart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

LUVAGROBART

Synonyms and Mappings

Resources