NINSIPAPOGENE SIBARNAREPVEC

UNII:	Y70X1GJT61
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	NINSIPAPOGENE SIBARNAREPVEC
GSRS Full Record:	Y70X1GJT61 i

2640294-04-6
HB-202 COMPONENT R3PICV-E7E6
NINSIPAPOGENE SIBARNAREPVEC [USAN]
Ninsipapogene Sibarnarepvec
RNA (attenuated replicating Pichinde virus vector HB-202 segment L), supramolecular complex with RNA (attenuated replicating Pichinde virus vector HB-202 segment S2 human papillomavirus 16 [24-glycine,26-glycine,91-glycine] gene E7 protein fusion protein with [69-glycine,112-glycine] gene E6 protein transgene plus membrane glycoprotein GPC-specifying), supramolecular complex with RNA (attenuated replicating Pichinde virus vector HB-202 segment S1 human papillomavirus 16 [24-glycine,26-glycine,91-glycine] gene E7 protein fusion protein with [69-glycine,112-glycine] gene E6 protein transgene plus nucleocapsid protein-specifying)
Recombinant replication-competent attenuated arenavirus (Pichinde virus [PICV]) vector with two copies of the small (S) genome segment (S RNA segment) with one encoding the viral membrane glycoprotein (GP) and one encoding the viral nucleocapsid protein (NP), and both encoding a synthetic human papillomavirus type 16 E7E6 fusion protein (with mutations of C24G, E26G and C91G in E7, and C69G and C112G in E6), and with a wild type large (L) genome segment (L RNA segment). Expression of the E7E6 fusion protein is under control of the viral expression mechanism

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

NINSIPAPOGENE SIBARNAREPVEC

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