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NAVEPEGRITIDE

UNII:Y3BH8M899D
Type:INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:NAVEPEGRITIDE
GSRS Full Record:
Y3BH8M899D
i

  • 2413551-27-4
  • ACP-015
  • C-Type natriuretic peptide (CNP), human, (89-126)-fragment (1-38) (CNP-38), conjugated at N6 of Lys26 with four O-methylpoly(ethylene glycol) chains (approx. 10 kDa each) via a cleavable tetra-antennary linker; L-leucyl-L-glutaminyl-L-α-glutamyl-L-histidyl-L-prolyl-L-asparaginyl-L-alanyl-L-arginyl-L-lysyl-L-tyrosyl-L-lysylglycyl-L-alanyl-L-asparaginyl-L-lysyl-L-lysylglycyl-L-leucyl-L-seryl-L-lysylglycyl-L-cysteinyl-L-phenylalanylglycyl-L-leucyl-N6-{N2-[N2,N6-bis(6-{[(3RS)-1-{3-[(3-{(2RS)-2,3-bis[α-methylpoly(oxyethylene)-ω-oxy]propoxy}propyl)amino]-3-oxopropyl}-2,5-dioxopyrrolidin-3-yl]sulfanyl}hexanoyl)-L-lysyl]-N2-methyl-N1-[2-(methylamino)ethyl]-L-isoasparaginyl}-L-lysyl-L-leucyl-L-α-aspartyl-L-arginyl-L-isoleucylglycyl-L-seryl-L-methionyl-L-serylglycyl-L-leucylglycyl-L-cysteine (22-38)-disulfide
  • NAVEPEGRITIDE [USAN]
  • Navepegritide
  • Poly(oxy-1,2-ethanediyl), α-hydro-ω-methoxy-, 26,26,26,26-tetraether with L-leucyl-L-glutaminyl-L-α-glutamyl-L-histidyl-L-prolyl-L-asparaginyl-L-alanyl-L-arginyl-L-lysyl-L-tyrosyl-L-lysylglycyl-L-alanyl-L-asparaginyl-L-lysyl-L-lysylglycyl-L-leucyl-L-seryl-L-lysylglycyl-L-cysteinyl-L-phenylalanylglycyl-L-leucyl-N<sup>6</sup>-[N<sup>2</sup>,N<sup>6</sup>-bis[6-[[1-[3-[[3-(2,3-dihydroxypropoxy)propyl]amino]-3-oxopropyl]-2,5-dioxo-3-pyrrolidinyl]thio]-1-oxohexyl]-L-lysyl-N<sup>2</sup>-methyl-N-[2-(methylamino)ethyl]-L-α-asparaginyl]-L-lysyl-L-leucyl-L-α-aspartyl-L-arginyl-L-isoleucylglycyl-L-seryl-L-methionyl-L-serylglycyl-L-leucylglycyl-L-cysteine cyclic (22→38)-disulfide
  • TRANSCON CNP
  • TRANSCON CNP-38
  • TRANSCON-C-TYPE NATRIURETIC PEPTIDE-38
  • YUVIWEL
  • navepegritide [INN]




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