ENZELKITUG

UNII:	X3XW6WQP6G
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	ENZELKITUG
GSRS Full Record:	X3XW6WQP6G i

2999644-88-9
ENZELKITUG [USAN]
Enzelkitug
H-gamma1 heavy chain humanized (1-449) [VH (Homo sapiens IGHV3-23*01 (81.6%) -(IGHD) -IGHJ3*02 (91.7%) M123>T (114), CDR-IMGT [8.7.13] (26-33.51-57.96-108)) (1-119) -Homo sapiens IGHG1*03v (100%) G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14 (CH1 R120>K (216) (120-217), hinge 1-15 (218-232), CH2 (233-342), CH3 E12 (358), M14 (360) (343-447), CHS (448-449)) (120-449)], (222-218')-disulfide with L-kappa light chain humanized (1'-218') [VKAPPA (Homo sapiens IGKV1-33*01 (87.8%) -IGKJ4*01 (100%), CDR-IMGT [6.3.13] (27'-32'.50'-52'.89'-101')) (1'-111')-Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPAA45.1 (157'), V101 (195')) (112'-218')]; dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa
Immunoglobulin G1, anti-(human CC chemokine receptor CCR8) (human-Oryctolagus cuniculus monoclonal RG6411 γ1-chain), disulfide with human-Oryctolagus cuniculus monoclonal RG6411 κ-chain, dimer
RO-7502175
RO-7502175 (HUMANIZED MONOCLONAL ANTIBODY BASED ON A HUMAN IMMUNOGLOBULIN G1 (AFUCOSYLATED IGG1) FRAMEWORK CONTAINING HEAVY CHAIN VH (GAMMA1) AND LIGHT CHAIN VL (KAPPA) SUBGROUP SEQUENCES)
RO7502175
enzelkitug [INN]
immunoglobulin G1-kappa, anti-[Homo sapiens CCR8 (C-C motif chemokine receptor 8, CKR-L1, CDw198) N-terminus], humanized monoclonal antibody

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

ENZELKITUG

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