AMESOTATUG

UNII:	WW5L89R6ZV
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	AMESOTATUG
GSRS Full Record:	WW5L89R6ZV i

3051777-50-2
Amesotatug
H-gamma1 heavy chain humanized (1-448) [VH (Homo sapiens IGHV1-69*10 (83.7%) -(IGHD) -IGHJ4*01 (93.3%) L123>M (113), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG1*01 (100%) G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (215) (119-216), hinge 1-15 (217-231), CH2 (232-341), CH3 D12 (357), L14 (359) (342-446), CHS (447-448)) (119-448)], (221-219')-disulfide with L-kappa light chain humanized (1'-219') [V-KAPPA (Homo sapiens IGKV2-30*02 (89.0%) -IGKJ2*01 (100%), CDR-IMGT [11.3.9] (27'-37'.55'-57'.94'-102')) (1'-112') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (158'), V101 (196')) (113'-219')]; dimer (227-227'':230-230'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44, glycoform alfa
Immunoglobulin G1, anti-(human annexin A1) (human-Mus musculus monoclonal MDX-124 γ1-chain), disulfide with human-Mus musculus monoclonal MDX-124 κ-chain, dimer
MDX-124
amesotatug [INN]
immunoglobulin G1-kappa, anti-[Homo sapiens ANXA1 (annexin A1, annexin 1, lipocortin 1)], humanized monoclonal antibody (amesotatug)

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

AMESOTATUG

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