LEXUCITUG

UNII:	WVR9WQ2A7W
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	LEXUCITUG
GSRS Full Record:	WVR9WQ2A7W i

3058391-51-5
DCSZ-11
H-gamma1 heavy chain humanized (1-450) [VH (Homo sapiens IGHV1-46*01 (86.7%) -(IGHD) -IGHJ3*01 (85.7%) Q120>A (112), M123>T (115), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG1*01 (100%) G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (217) (121-218), hinge 1-15 (219-233), CH2 (234-343), CH3 D12 (359), L14 (361) (344-448), CHS (449-450)) (121-450)], (223-218')-disulfide with L-kappa light chain humanized (1'-218') [V-KAPPA (Homo sapiens IGKV1-5*03 (86.5%) -IGKJ4*01 (90.9%) V124>L (108'), CDR-IMGT [10.3.9] (27'-36'.54'-56'.93'-101')) (1'-111') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (157'), V101 (195')) (112'-218')]; dimer (229-229'':232-232'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa
Immunoglobulin G1, anti-(human CD93 antigen) (human-Mus musculus monoclonal DCSZ11 γ-chain), disulfide with human-Mus musculus monoclonal DCSZ11 κ-chain, dimer
Lexucitug
immunoglobulin G1-kappa, anti-[Homo sapiens CD93 (complement component C1q receptor 1, C1qR1)], humanized monoclonal antibody (lexucitug)
lexucitug [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

LEXUCITUG

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