INVIMESTROCEL

UNII:	WNR9FH307P
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	INVIMESTROCEL
GSRS Full Record:	WNR9FH307P i

HLCM-051
HLCM051
Invimestrocel
Invimestrocel (Allogeneic human multipotent adult progenitor cells (MAPC) derived from bone marrow and isolated by density gradient centrifugation. The cells are expanded ex vivo on fibronectin-coated surfaces under low-oxygen conditions and in the presence of growth media for the creation of a master cell bank (passage 4), a working cell bank (passage 6) and active substance (passage 9). The cells are adherent, secrete proangiogenic factors (including VEGF, IL-8 and CXCL5) and of mesenchymal progenitor lineage (in vitro differentiation to endothelial, hepatic and neuronal lineages). The cells express CD49c and CD90 (≥ 95% of the cells), and lack expression of CD45 and HLA II (<5%). Additional markers include >90% CD13, CD44, CD73, CD105 and <5% CD34)
MAPC
MULTIPOTENT ADULT PROGENITOR CELLS
MULTIPOTENT ADULT PROGENITOR CELLS (BONE MARROW DERIVED)
MULTISTEM
invimestrocel [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

INVIMESTROCEL

Synonyms and Mappings

Resources