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ACAZICOLCEPT

UNII:W507556HV0
Formula:
Preferred Substance Name:ACAZICOLCEPT
GSRS Full Record:
W507556HV0
i

  • 2270247-50-0
  • 1-122-INDUCIBLE COSTIMULATORY LIGAND PROTEIN (52-HISTIDINE,57-TYROSINE,100-ARGININE) (HUMAN) FUSION PROTEIN WITH SYNTHETIC PEPTIDE LINKER (GGGGSGGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN .GAMMA.1-CHAIN C REGION VARIANT C-TERMINAL FRAGMENT), DIMER
  • ACAZICOLCEPT [INN]
  • ACAZICOLCEPT [USAN]
  • ACAZICOLCEPT [WHO-DD]
  • ALPN-101
  • HUMAN INDUCIBLE T-CELL CO-STIMULATOR LIGAND (ICOS LIGAND) N-TERMINAL FRAGMENT (1-122) (VARIANT (N52>H, N57>Y, Q100>R), FUSED VIA PEPTIDYL LINKER 123GGGGSGGGGS132 TO A HUMAN IMMUNOGLOBULIN G1 FC FRAGMENT (133-363) VARIANT (C137>S, L151>A, L152>E, G154>A, C-TERMINAL K364 DELETED), DIMER, GLYCOSYLATED, PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS; (N52>H, N57>Y, Q100>R) HUMAN INDUCIBLE T-CELL COSTIMULATOR LIGAND (ICOS LIGAND, ICOSL, CD275) N-TERMINAL FRAGMENT (1-122) FUSED VIA A (G4S)2 LINKER (123-132) TO A HUMAN IMMUNOGLOBULIN G1 C-TERMINAL K>DEL FC FRAGMENT (133-363) (HOMO SAPIENS IGHG1*01; HINGE 133-147 (C137>S); CH2 148-257 (L151A, L152E, G154A); CH3 258-362; CHS 363), DIMER (143-143':146-146')-BISDISULFIDE, PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, GLYCOFORM ALFA




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