SUSITABART

UNII:	V2AZ4VD49V
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	SUSITABART
GSRS Full Record:	V2AZ4VD49V i

3095642-29-5
Gamma1 heavy chain humanized (1-450) [VH (Homo sapiens IGHV1-18*01 (85.7%) -(IGHD) -IGHJ4*01 (93.3%), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1, CH1 K120, CH3 E12, M14, 6-G1v14-1 CH2 A1.3, A1.2, A1, 9-G1v21 CH2 Y15.1, T16, E18, 16-G1v116 C84.4 (CH1 R120>K (217) (121-218), hinge 1-15 (219-233), CH2 L1.3>A (237), L1.2>A (238), G1>A (240), M15.1>Y (255), S16>T (257), T18>E (259), N84.4>C (300) (234-343), CH3 E12 (359), M14 (361) (344-448), CHS (449-450)) (121-450)], (223-213')-disulfide with L-kappa light chain humanized (1'-213') [V-KAPPA (Homo sapiens IGKV3-11*02 (85.3%) -IGKJ4*01 (100%), CDR-IMGT [5.3.9] (27'-31'.49'-51'.88'-96')) (1'-106') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (152'), V101 (190')) (107'-213')]; dimer (229-229'':232-232'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44, nonglycosylated
Immunoglobulin G1 [237-alanine,238-alanine,240-alanine,255-tyrosine,257-threonine,259-glutamic acid,300-cysteine], anti-(human transmembrane protein TM4SF1) (human-Mus musculus monoclonal AN46 γ1-chain), disulfide with human-Mus musculus monoclonal AN46 κ-chain, dimer
Immunoglobulin G1-kappa, anti-[Homo sapiens TM4SF1 (transmembrane 4 L6 family member 1)], humanized monoclonal antibody
Susitabart
susitabart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

SUSITABART

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