LASREKIBART

UNII:	UP8FP5L8D6
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	LASREKIBART
GSRS Full Record:	UP8FP5L8D6 i

3021525-26-5
H-gamma1 heavy chain humanized (1-448) [VH (Homo sapiens IGHV3-23*02 (88.7%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, CH3 D12, L14, 9-G1v21 CH2 Y15.1, T16, E18 (CH1 K120 (215) (119-216), hinge 1-15 (217-231), CH2 M15.1>Y (253), S16>T (255), T18>E (257) (232-341), CH3 D12 (357), L14 (359) (342-446), CHS (447-448)) (119-448)], (221-214')-disulfide with L-kappa light chain humanized (1'-214')[V-KAPPA (Homo sapiens IGKV1-6*01 (84.0%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (227-227'':230-230'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa
Immunoglobulin G1 [253-tyrosine,255-threonine,257-glutamic acid], anti-(human interleukin-5) (human-Rattus norvegicus monoclonal HRP00488 γ1-chain), disulfide with human-Rattus norvegicus monoclonal HRP00488 κ-chain, dimer
Lasrekibart
immunoglobulin G1-kappa, anti-[Homo sapiens IL5 (interleukin 5, IL-5)], humanized monoclonal antibody (lasrekibart)
lasrekibart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

LASREKIBART

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