EFDORALPRIN ALFA

UNII:	TYK0A4WR1D
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	EFDORALPRIN ALFA
GSRS Full Record:	TYK0A4WR1D i

2539844-42-1
Efdoralprin Alfa
IgG4 Fc linked recombinant human alpha-1 antitrypsin
efdoralprin alfa [INN]
human alpha-1-antitrypsin (alpha-1 protease inhibitor, serpin A1, AAT) (1-394), variant (M351>E, M358>L) fused via peptide linker 395GS396 to an Fc fragment of human immunoglobulin G4 (397-625) [Homo sapiens IGHG4*01, hinge S406>P (397-408), CH2 L413>E, M430>Y (409-518), CH3 M606>L (519-623), CHS (624-625)]; dimer (404-407', 407-404')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO DG44, glycoform alfa
α1-Antitrypsin [351-glutamic acid,358-leucine] (human) fusion protein with peptide linker (GS) fusion protein with immunoglobulin G4 [406-proline,413-glutamic acid,430-tyrosine,606-leucine] (human γ4-chain C region C-terminal fragment), dimer

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

EFDORALPRIN ALFA

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