SELCODEBART

UNII:	TQU847U6D9
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	SELCODEBART
GSRS Full Record:	TQU847U6D9 i

3038196-66-3
DISC-0974
DMN1A-S04
H-gamma1 heavy chain humanized (1-445) [VH (Homo sapiens IGHV3-30*02 (88.8%) -(IGHD) -IGHJ1*01 (100%), CDR-IMGT [8.8.8] (26-33.51-58.97-104)) (1-115) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14, 6-G1v14 CH2 A1.3, A1.2 (CH1 R120>K(212) (116-213), hinge 1-15 (214-228), CH2 L1.3>A (232), L1.2>A (233) (229-338), CH3 E12 (354), M14 (356) (339-443), CHS (444-445)) (116-445)], (218-219')-disulfide with L-kappa light chain humanized (1'-219') [V-KAPPA (Homo sapiens IGKV2-30*02 (87.0%) -IGKJ2*01 (100%), CDR-IMGT [11.3.9] (27'-37'.55'-57'.94'-102')) (1'-112') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (158'), V101 (196')) (113'-219')]; dimer (224-224'': 227-227'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44, glycoform alfa
H5F9-AM8
Immunoglobulin G1 [232-alanine,233-alanine], anti-(human repulsive guidance molecule A and hemojuvelin) (human-Rattus norvegicus monoclonal DISC-0974 γ1-chain), disulfide with human-Rattus norvegicus monoclonal DISC-0974 κ-chain, dimer
Immunoglobulin G1 [232-alanine,233-alanine], anti-(human repulsive guidance molecule A) (human-Rattus norvegicus monoclonal DISC-0974 γ1-chain), disulfide with human-Rattus norvegicus monoclonal DISC-0974 κ-chain, dimer
RGMA H5F9PJP297 / PJP298 HIGG1 / K MUT
RGMAH5F9AM.8
SELCODEBART [USAN]
Selcodebart
immunoglobulin G1-kappa, anti-[Homo sapiens HJV (hemojuvelin, hemochromatosis type 2 protein, HFE2, repulsive guidance molecule C, RGMC)], humanized monoclonal antibody (Selcodebart)
selcodebart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

SELCODEBART

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