FDA official logo
GSRS logoPFDA official logo

MODAKAFUSP ALFA

UNII:TN8CEX4UT2
Type:INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:MODAKAFUSP ALFA
GSRS Full Record:
TN8CEX4UT2
i

  • 2254522-19-3
  • ANTI-CD38-TARGETED IGG4-ATTENUATED IFNA TAK-573
  • IMMUNOGLOBULIN G4 (228-PROLINE), ANTI-(HUMAN ANTIGEN CD38) (HUMAN-RATTUS NORVEGICUS MONOCLONAL TAK-573 .GAMMA.4-CHAIN) FC C-TERMINAL FUSION PROTEIN WITH HUMAN INTERFERON .ALPHA.2B (106-ALANINE,145-ASPARTIC ACID), DISULFIDE WITH HUMAN-RATTUS NORVEGICUS MONOCLONAL TAK-573 .KAPPA.-CHAIN, DIMER
  • IMMUNOGLOBULIN G4-KAPPA, ANTI-(HUMAN ADP-RIBOSYL CYCLASE/CYCLIC ADP-RIBOSE HYDROLASE 1 (EC:3.2.2.6) (ADPRC 1/CADRP HYDROLASE 1, CELL SURFACE ANTIGEN CD38)), HUMANIZED MONOCLONAL ANTIBODY, FUSED AT EACH C-TERMINUS OF THE HEAVY CHAINS (1-447, 1''-447'') TO ATTENUATED HUMAN INTERFERON .ALPHA.-2B (IFN.ALPHA.2B) VARIANT (K23>R470, T106>A553, A145>D592) (448-612, 448''-612''); GAMMA4 HEAVY CHAIN HUMANIZED FUSED TO IFN.ALPHA.2B (1-612) (VH (HOMO SAPIENS IGHV1-69-2*01 (90.7%)-(IGHD)-IGHJ4*01 (85.7%)) CDRIMGT (8.8.13) (26-33.51-58.97-109) (1-120)-HOMO SAPIENS IGHG4*01, G4V5 H P10 (CH1 (121-218), HINGE 1-12 S10>P (228) (219-230), CH2 (231-340), CH3 (341-445), CHS (446-447))(121-447), FUSED TO IFN.ALPHA.2B K23>R (470), T106>A (553), A145>D (592) (448-612)),(134-214')-DISULFIDE WITH KAPPA LIGHT CHAIN HUMANIZED (1'-214') (V-KAPPA (HOMO SAPIENS IGKV1-33*01 (83.2%)-IGKJ4*01 (100%)) CDR-IMGT (6.3.9) (27-32.50-52.89-97) (1'-107')-HOMO SAPIENS IGKC*01 (100%), KM3 A45.1 (153), V101 (191) (108'-214')); DIMER (226-226'':229-229'')-BISDISULFIDE; PRODUCED IN CHINESE HAMSTER OVARY (CHO) K1SV CELLS, GLYCOFORM ALFA
  • MODAKAFUSP ALFA [USAN]
  • Modakafusp alfa [WHO-DD]
  • TAK-573
  • TAK573
  • TEV-48573
  • modakafusp alfa [INN]




UNII - TN8CEX4UT2 | UNII Search Service