CRETOSTIMOGENE GRENADENOREPVEC

UNII:	THP9ML4NTZ
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	CRETOSTIMOGENE GRENADENOREPVEC
GSRS Full Record:	THP9ML4NTZ i

2414312-87-9
CG-0070
CG0070
CG0070 GENOME STRUCTURE COMPRISES A LEFT ITR (5' ITR), A POLYA SEQUENCE, AN E2F RESPONSIVE PROMOTER LINKED TO THE ADENOVIRAL E1A CODING REGION, A HETEROLOGOUS CODING SEQUENCE ENCODING GM-CSF, AND A RIGHT ITR (3' ITR) AND CARRIES MOST OF THE WILD-TYPE HUMAN ADENOVIRUS AD5 GENOME (GENBANK: AY339865.1), EXCEPT FOR THE FOLLOWING REGIONS: (1) THE ENDOGENOUS PROMOTER OF THE ESSENTIAL EARLY GENE E1A HAS BEEN REPLACED BY HUMAN E2F-1 PROMOTER (GENBANK ACCESSION NO. AF516106.1), (2) A SV40 LATE POLYADENYLATION SIGNAL HAS BEEN PLACED UPSTREAM TO THE HE2F-1 PROMOTER, AND (3) E3 GP19KD-CODING REGION HAS BEEN REPLACED BY HUMAN GM-CSF CDNA SEQUENCE (ACCESSION NO. NM_000758.3)
CRETOSTIMOGENE GRENADENOREPVEC [USAN]
Cretostimogene Grenadenorepvec
Cretostimogene grenadenorepvec [WHO-DD]
cretostimogene grenadenorepvec [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

CRETOSTIMOGENE GRENADENOREPVEC

Synonyms and Mappings

Resources