DALVAPRUBART

UNII:	T8N233T5YS
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	DALVAPRUBART
GSRS Full Record:	T8N233T5YS i

2766342-51-0
Dalvaprubart
H-gamma1 heavy chain Homo sapiens (1-452) [VH(Homo sapiens IGHV3-9*01 (97.0%) -(IGHD)-IGHJ6*01(100%), CDR-IMGT [8.8.15] (26-33.51-58.97-111)) (1-122)-Homo sapiens IGHG1*01, G1m17,1 CH1 K120, CH3 D12, L14, G1CH1_10-17_3giz G10, S12, K13, S14, T15, S16 (CH1 K120 (219), S10>G (136), K12>S (138), S13>K (139), T14>S (140), S15>T (141), G16>S (142) (123-220), hinge 1-15 (221-235), CH2 (236-345), CH3 D12 (361), L14 (363) (346-450), CHS (451-452)) (123-452)], (225-214')-disulfide with L-kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV3-11*01 (100%) -IGKJ5*01 (100%), CDR-IMGT [6.3.9](27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (231-231'':234-234'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, lacking the enzyme alpha-(1,6)-fucosyltransferase (FUT8-KO), glycoform alfa
Immunoglobulin G1, anti-(human CD20 antigen) (human-Mus musculus monoclonal BAT4406F γ1-chain), disulfide with human-Mus musculus monoclonal BAT4406F κ-chain, dimer
dalvaprubart [INN]
immunoglobulin G1-kappa, anti-[Homo sapiens MS4A1 (membrane-spanning 4-domains subfamily A member 1, CD20)], Homo sapiens monoclonal antibody (dalvaprubart)

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

DALVAPRUBART

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