CORVELDEBART

UNII:	T3QQ78A6U1
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	CORVELDEBART
GSRS Full Record:	T3QQ78A6U1 i

3062245-47-7
Corveldebart
H-gamma1 heavy chain humanized (1-449) [VH (Homo sapiens IGHV1-46*01 (84.5%) -(IGHD) -IGHJ4*01 (93.3%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*03, G1m3, nG1m1 CH1 R120, CH3 E12, M14, 6-G1v14 CH2 A1.3, A1.2 (CH1 R120 (216) (120-217), hinge 1-15 (218-232), CH2 L1.3>A (236), L1.2>A (237) (233-342), CH3 E12 (358), M14 (360) (343-447), CHS (448-449)) (120-449)], (222-214')-disulfide with L-kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV3-15*01 (80.0%) -IGKJ1*01 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (228-228'':231-231'')-bisdisulfide, produced in a cell line of Chinese hamster ovary (CHO) cells, derived from the cell line CHO-K1, glycoform alfa
Immunoglobulin G1 [236-alanine,237-alanine], anti-(human angiopoietin-like protein 4) (human-Mus musculus monoclonal MAR001 γ1-chain), disulfide with human-Mus musculus monoclonal MAR001 κ-chain, dimer
corveldebart [INN]
immunoglobulin G1-kappa, anti-[Homo sapiens ANGPTL4 (angiopoietin like 4)], humanized monoclonal antibody (corveldebart)

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

CORVELDEBART

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