EXERENIBART

UNII:	T2CP32988Q
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	EXERENIBART
GSRS Full Record:	T2CP32988Q i

2996101-49-4
Exerenibart
Immunoglobulin G4 [232-proline], anti-(human/Macaca fascicularis/Mus musculus/Rattus norvegicus transmembrane serine proteinase 6) (human monoclonal REGN7999 γ4-chain), disulfide with human monoclonal REGN7999 κ-chain, dimer
REGN-7999
REGN7999
exerenibart [INN]
immunoglobulin G4-kappa, anti-[Homo sapiens TMPRSS6 (transmembrane serine protease 6, matriptase-2, MT2)], Homo sapiens monoclonal antibody; H-gamma4 heavy chain Homo sapiens (1-451) [VH (Homo sapiens IGHV3-23*04 (95.9%) -(IGHD) -IGHJ1*01 (90.9%) L123>T (119), CDR-IMGT [8.8.17] (26-33.51-58.97-113)) (1-124) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, 12-G4v5 h P10 (CH1 (125-222), hinge 1-12 S10>P (232) (223-234), CH2 L92 (313) (235-344), CH3 (345-449), CHS (450-451)) (125-451)], (138-214')-disulfide with L-kappa light chain Homo sapiens (1'-214') [VKAPPA (Homo sapiens IGKV1-12*01 (92.6%) -IGKJ3*01 (100%), CDRIMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (230-230'':233-233'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

EXERENIBART

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