FITUSIRAN

UNII:	SV9W47ZLE1
Formula:
Preferred Substance Name:	FITUSIRAN

1499251-18-1
ALN-57213
ALN-AT3SC
FITUSIRAN [INN]
FITUSIRAN [USAN]
FITUSIRAN [WHO-DD]
RNA, ((2'-DEOXY-2'-FLUORO)G-SP-GM-SP-(2'-DEOXY-2'-FLUORO)U-UM-(2'-DEOXY-2'-FLUORO)A-AM-(2'-DEOXY-2'-FLUORO)C-AM-(2'-DEOXY-2'-FLUORO)C-(2'-DEOXY-2'-FLUORO)C-(2'-DEOXY-2'-FLUORO)A-UM-(2'-DEOXY-2'-FLUORO)U-UM-(2'-DEOXY-2'-FLUORO)A-CM-(2'-DEOXY-2'-FLUORO)U-UM-(2'-DEOXY-2'-FLUORO)C-AM-(2'-DEOXY-2'-FLUORO)A), 3'-(((2S,4R)-1-(29-((2-(ACETYLAMINO)-2-DEOXY-.BETA.-D-GALACTOPYRANOSYL)OXY)-14,14-BIS((3-((3-((5-((2-(ACETYLAMINO)-2-DEOXY-.BETA.-D-GALACTOPYRANOSYL)OXY)-1-OXOPENTYL)AMINO)PROPYL)AMINO)-3-OXOPROPOXY)METHYL)-1,12,19,25-TETRAOXO-16-OXA-13,20,24-TRIAZANONACOS-1-YL)-4-HYDROXY-2-PYRROLIDINYL)METHYL HYDROGEN PHOSPHATE), COMPLEX WITH RNA (UM-SP-(2'-DEOXY-2'-FLUORO)U-SP-GM-(2'-DEOXY-2'-FLUORO)A-AM-(2'-DEOXY-2'-FLUORO)G-UM-(2'-DEOXY-2'-FLUORO)A-AM-(2'-DEOXY-2'-FLUORO)A-UM-GM-GM-(2'-DEOXY-2'-FLUORO)U-GM-(2'-DEOXY-2'-FLUORO)U-UM-(2'-DEOXY-2'-FLUORO)A-AM-(2'-DEOXY-2'-FLUORO)C-CM-SP-AM-SP-GM)
SMALL INTERFERING RNA (SIRNA) INHIBITING ANTITHROMBIN LIVER PRODUCTION: DUPLEX OF ((2S,4R)-1-(1-((2-ACETAMIDO-2-DEOXY-.BETA.-D-GALACTOPYRANOSYL)OXY)-16,16-BIS((3-((3-(5-((2-ACETAMIDO-2-DEOXY-.BETA.-D-GALACTOPYRANOSYL)OXY)PENTANAMIDO)PROPYL)AMINO)-3-OXOPROPOXY)METHYL)-5,11,18-TRIOXO-14-OXA-6,10,17-TRIAZANONACOSAN-29-OYL)-4-HYDROXYPYRROLIDIN-2-YL)METHYL HYDROGEN (ALL-P-AMBO)-2'-DEOXY-2'-FLUORO-P-THIOGUANYLYL-(3'->5')-2'-O-METHYL-P-THIOGUANYLYL-(3'->5')-2'-DEOXY-2'-FLUOROURIDYLYL-(3'->5')-2'-O-METHYLURIDYLYL-(3'->5')-2'-DEOXY-2'-FLUOROADENYLYL-(3'->5')-2'-O-METHYLADENYLYL-(3'->5')-2'-DEOXY-2'-FLUOROCYTIDYLYL-(3'->5')-2'-O-METHYLADENYLYL-(3'->5')-2'-DEOXY-2'-FLUOROCYTIDYLYL-(3'->5')-2'-DEOXY-2'-FLUOROCYTIDYLYL-(3'->5')-2'-DEOXY-2'-FLUOROADENYLYL-(3'->5')-2'-O-METHYLURIDYLYL-(3'->5')-2'-DEOXY-2'-FLUOROURIDYLYL-(3'->5')-2'-O-METHYLURIDYLYL-(3'->5')-2'-DEOXY-2'-FLUOROADENYLYL-(3'->5')-2'-O-METHYLCYTIDYLYL-(3'->5')-2'-DEOXY-2'-FLUOROURIDYLYL-(3'->5')-2'-O-METHYLURIDYLYL-(3'->5')-2'-DEOXY-2'-FLUOROCYTIDYLYL-(3'->5')-2'-O-METHYLADENYLYL-(3'->5')-2'-DEOXY-2'-FLUOROADENYLATE AND (ALL-P-AMBO)-2'-O-METHYL-P-THIOURIDYLYL-(3'->5')-2'-DEOXY-2'-FLUORO-P-THIOURIDYLYL-(3'->5')-2'-O-METHYLGUANYLYL-(3'->5')-2'-DEOXY-2'-FLUOROADENYLYL-(3'->5')-2'-O-METHYLADENYLYL-(3'->5')-2'-DEOXY-2'-FLUOROGUANYLYL-(3'->5')-2'-O-METHYLURIDYLYL-(3'->5')-2'-DEOXY-2'-FLUOROADENYLYL-(3'->5')-2'-O-METHYLADENYLYL-(3'->5')-2'-DEOXY-2'-FLUOROADENYLYL-(3'->5')-2'-O-METHYLURIDYLYL-(3'->5')-2'-O-METHYLGUANYLYL-(3'->5')-2'-O-METHYLGUANYLYL-(3'->5')-2'-DEOXY-2'-FLUOROURIDYLYL-(3'->5')-2'-O-METHYLGUANYLYL-(3'->5')-2'-DEOXY-2'-FLUOROURIDYLYL-(3'->5')-2'-O-METHYLURIDYLYL-(3'->5')-2'-DEOXY-2'-FLUOROADENYLYL-(3'->5')-2'-O-METHYLADENYLYL-(3'->5')-2'-DEOXY-2'-FLUOROCYTIDYLYL-(3'->5')-2'-O-METHYL-P-THIOCYTIDYLYL-(3'->5')-2'-O-METHYL-P-THIOADENYLYL-(3'->5')-2'-O-METHYLGUANOSINE

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UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

FITUSIRAN

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