LIXUDEBART

UNII:	STN3UZ6YBJ
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	LIXUDEBART
GSRS Full Record:	STN3UZ6YBJ i

2749515-10-2
ALE.F02
Gamma1 heavy chain humanized (1-448) [VH (Homo sapiens IGHV3-21*01 (94.9%) -(IGHD) -IGHJ1*01 (92.9%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*03, G1m3, nG1m1 CH1 R120, CH3 E12, M14, CH2 IGHG1v39 CH2 F1.3, E1.2, S116 (CH1 R120 (216) (120-217), hinge 1-15 (218-232), CH2 L1.3>F (236) , L1.2>E (237), P116>S (333) (233-342), CH3 E12 (358), M14 (360) (343-447), CHS K2>del (448)) (120-448)], (222-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV3-15*01 (84.2%) -IGKJ1*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107')-Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa
Immunoglobulin G1 [236-phenylalanine,237-glutamic acid,333-serine,de-449-lysine], anti-(human claudin-1) (human-Rattus norvegicus monoclonal ALE.F02 γ1-chain), disulfide with human-Rattus norvegicus monoclonal ALE.F02 κ-chain, dimer
LIXUDEBART [USAN]
Lixudebart
RECOMBINANT HUMANISED IgG1 KAPPA ANTI-CLDN1 MONOCLONAL ANTIBODY ALE.F02
lixudebart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

LIXUDEBART

Synonyms and Mappings

Resources