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GIVOSIRAN

UNII:ROV204583W
Formula:
Preferred Substance Name:GIVOSIRAN

  • 1639325-43-1
  • ALN-AS1
  • DUPLEX OF ((2S,4R)-1-(1-((2-ACETAMIDO-2-DEOXY-.BETA.-D-GALACTOPYRANOSYL)OXY)-16,16-BIS((3-((3-(5-((2-ACETAMIDO-2-DEOXY-.BETA.-D-GALACTOPYRANOSYL)OXY)PENTANAMIDO)PROPYL)AMINO)-3- OXOPROPOXY)METHYL)-5,11,18-TRIOXO-14-OXA-6,10,17-TRIAZANONACOSAN-29-OYL)-4-HYDROXYPYRROLIDIN-2-YL)METHYL HYDROGEN (ALL-P-AMBO)-2'-O-METHYL-P-THIOCYTIDYLYL-(3' 5')- 2'-O-METHYL-P-THIOADENYLYL-(3' 5')-2'-O-METHYLGUANYLYL-(3' 5')-2'-O-METHYLADENYLYL- (3' 5')-2'-O-METHYLADENYLYL-(3' 5')-2'-O-METHYLADENYLYL-(3' 5')-2'-DEOXY-2'-FLUOROGUANYLYL-(3' 5')-2'-O-METHYLADENYLYL-(3' 5')-2'-DEOXY-2'-FLUOROGUANYLYL-(3' 5')-2'- O-METHYLURIDYLYL-(3' 5')-2'-DEOXY-2'-FLUOROGUANYLYL-(3' 5')-2'-O-METHYLURIDYLYL-(3' 5')-2'-DEOXY-2'-FLUOROCYTIDYLYL-(3' 5')-2'-O-METHYLURIDYLYL-(3' 5')-2'-DEOXY-2'-FLUOROCYTIDYLYL- (3' 5')-2'-O-METHYLADENYLYL-(3' 5')-2'-O-METHYLURIDYLYL-(3' 5')-2'-O-METHYLCYTIDYLYL-(3' 5')-2'-O-METHYLURIDYLYL-(3' 5')-2'-O-METHYLURIDYLYL-(3' 5')-2'-O-METHYL-3'-ADENYLATE AND (ALL-P-AMBO)-2'-O-METHYL-P-THIOURIDYLYL-(5' 3')-2'-O-METHYL-P-THIOGUANYLYL-(5' 3')- 2'-O-METHYLGUANYLYL-(5' 3')-2'-DEOXY-2'-FLUOROURIDYLYL-(5' 3')-2'-O-METHYLCYTIDYLYL- (5' 3')-2'-DEOXY-2'-FLUOROURIDYLYL-(5' 3')-2'-O-METHYLURIDYLYL-(5' 3')-2'-DEOXY-2'- FLUOROURIDYLYL-(5' 3')-2'-O-METHYLCYTIDYLYL-(5' 3')-2'-DEOXY-2'-FLUOROURIDYLYL-(5' 3')-2'-OMETHYLCYTIDYLYL-( 5' 3')-2'-DEOXY-2'-FLUOROADENYLYL-(5' 3')-2'-O-METHYLCYTIDYLYL-(5' 3')-2'-DEOXY-2'-FLUOROADENYLYL-(5' 3')-2'-O-METHYLGUANYLYL-(5' 3')-2'-DEOXY-2'-FLUOROADENYLYL- (5' 3')-2'-O-METHYLGUANYLYL-(5' 3')-2'-DEOXY-2'-FLUOROURIDYLYL-(5' 3')-2'-OMETHYLADENYLYL-( 5' 3')-2'-DEOXY-2'-FLUOROGUANYLYL-(5' 3')-2'-DEOXY-2'-FLUORO-PTHIOADENYLYL-( 5' 3')-2'-DEOXY-2'-FLUORO-P-THIOADENYLYL-(5' 3')-2'-O-METHYLURIDINE
  • GIVOSIRAN [INN]
  • GIVOSIRAN [MI]
  • GIVOSIRAN [USAN]
  • GIVOSIRAN [WHO-DD]
  • RNA, (CM-SP-AM-SP-GM-AM-AM-AM-(2'-DEOXY-2'-FLUORO)G-AM-(2'-DEOXY-2'-FLUORO)G-UM-(2'-DEOXY-2'-FLUORO)G-UM-(2'-DEOXY-2'-FLUORO)C-UM-(2'-DEOXY-2'-FLUORO)C-AM-UM-CM-UM-UM-AM), 3'-(((2S,4R)-1-(29-((2-(ACETYLAMINO)-2-DEOXY-.BETA.-D-GALACTOPYRANOSYL)OXY)- 14,14-BIS((3-((3-((5-((2-(ACETYLAMINO)-2-DEOXY- -D-GALACTOPYRANOSYL)OXY)-1-OXOPENTYL)AMINO)PROPYL)AMINO)-3-OXOPROPOXY)METHYL)-1,12,19,25-TETRAOXO-16-OXA- 13,20,24-TRIAZANONACOS-1-YL)-4-HYDROXY-2-PYRROLIDINYL)METHYL HYDROGEN PHOSPHATE), COMPLEX WITH RNA (UM-SP-(2'-DEOXY-2'-FLUORO)A-SP-(2'-DEOXY-2'-FLUORO)A-(2'-DEOXY-2'- FLUORO)G-AM-(2'-DEOXY-2'-FLUORO)U-GM-(2'-DEOXY-2'-FLUORO)A-GM-(2'-DEOXY-2'-FLUORO)ACM-( 2'-DEOXY-2'-FLUORO)A-CM-(2'-DEOXY-2'-FLUORO)U-CM-(2'-DEOXY-2'-FLUORO)U-UM-(2'- DEOXY-2'-FLUORO)U-CM-(2'-DEOXY-2'-FLUORO)U-GM-SP-GM-SP-UM) (1:1)




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