CILETATUG

UNII:	RAZ26CB689
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	CILETATUG
GSRS Full Record:	RAZ26CB689 i

2897622-41-0
Ciletatug
H-gamma1 heavy chain humanized (1-449) [VH (Homo sapiens IGHV1-46*01 (86.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*03v (100%) G1m3>G1m17, nG1m1, CH1 K120, CH3 E12, M14 (CH1 R120>K (216) (120-217), hinge 1-15 (218-232), CH2 (233-342), CH3 E12 (358), M14 (360) (343-447), CHS (448-449)) (120-449)], (222-220')-disulfide with L-kappa light chain humanized (1'-220') [V-KAPPA (Homo sapiens IGKV2-28*01 (85.1%) -IGKJ4*01 (100%), CDR-IMGT [12.3.9] (27'-38'.56'-58'.95'-103')) (1'-113') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (159'), V101 (197')) (114'-220')]; dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa
Immunoglobulin G1, anti-(human/Macaca fascicularis/Mus musculus/Canis familiaris/Rattus norvegicus claudin CLDN18.2) (human-Mus musculus monoclonal RC118-B186314B11S γ1-chain), disulfide with human-Mus musculus monoclonal RC118-B186314B11S κ-chain, dimer
ciletatug [INN]
immunoglobulin G1-kappa, anti-[Homo sapiens CLDN18 (claudin 18, claudin-18, surfactant associated protein J, SFTPJ) isoform 2], humanized monoclonal antibody (Ciletatug)

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

CILETATUG

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