GASPANTATUG

UNII:	R8EYZ84V2J
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	GASPANTATUG
GSRS Full Record:	R8EYZ84V2J i

3004869-54-6
Gaspantatug
H-gamma1 heavy chain Homo sapiens (1-448) [VH (Homo sapiens IGHV1-46*01 (78.6%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG1*03v (100%) G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14 (CH1 R120>K (215) (119-216), hinge 1-15 (217-231), CH2 (232-341), CH3 E12 (357), M14 (359) (342-446), CHS (447-448)) (119-448)], (221-220')-disulfide with L-kappa light chain Homo sapiens (1'-220') [V-KAPPA (Homo sapiens IGKV4-1*01(86.1%) -IGKJ1*01 (91.7%), CDR-IMGT [12.3.9] (27'-38'.56'-58'.95'-103')) (1'-113') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (159'), V101 (197')) (114'-220')], dimer (227-227'':230-230'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, lacking the enzyme alpha-(1,6)-fucosyltransferase (FUT8-KO), glycoform alfa
Immunoglobulin G1, anti-(human claudin CLDN18.2) (human monoclonal M108 γ1-chain), disulfide with human monoclonal M108 κ-chain, dimer
gaspantatug [INN]
immunoglobulin G1-kappa, anti-[Homo sapiens CLDN18 (claudin 18, claudin-18, surfactant associated protein J, SFTPJ) isoform 2], Homo sapiens monoclonal antibody (gaspantatug)

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

GASPANTATUG

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