DOVIPEGLEUKIN

UNII:	R55C9TF7AB
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	DOVIPEGLEUKIN
GSRS Full Record:	R55C9TF7AB i

3076365-91-5
2-133-Interleukin 2 [125-serine] (recombinant human SAR444336), 16-[N6-[[2-[8,9-dihydro-8-[4-[(2-hydroxyethyl)amino]-1,4-dioxobutyl]-1H(or 3H)-benzo[c]-1,2,3-triazolo[4,5-e][1]benzazocin-1(or 3)-yl]ethoxy]carbonyl]-L-lysine], 16-ether with α-methyl-ω-hydroxypoly(oxy-1,2-ethanediyl (50000 Da)
Dovipegleukin
dovipegleukin [INN]
human interleukin 2 (IL2, IL-2, T-cell growth factor (TCGF); Uniprot: P60568) fragment (2-133 in the current sequence), variant (H16>N6 (2-azidoethoxy)-carbonyl-L-lysine, C125>S) to allow for a site-specific pegylation at position 16 with a {2-[8-(4-{[α-methylpoly(oxyethylene)-ω-yl]amino}-4-oxobutanoyl)-8,9-dihydro-1H (or 3H)-dibenzo[b,f][1,2,3]triazolo[4,5-d]azocin-1 (or 3)-yl]ethoxy}carbonyl group, produced in Escherichia coli strain BL21(DE3), not glycosylated

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

DOVIPEGLEUKIN

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