PRODUVOFUSP

UNII:	R2Z6HC43VT
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	PRODUVOFUSP
GSRS Full Record:	R2Z6HC43VT i

2925698-93-5
1-305-Complement factor H (human) fusion protein with immunoglobulin (human-Lama glama single-domain VHH fragment) fusion protein with peptide linker (GGGGA) fusion protein with peptide (synthetic poly-RGD-containing integrin recognition domain)
Produvofusp
human complement factor H (H factor 1, CFH) catalytic domain containing fragment (1-305) fused to a humanized heavy chain variable domain only (VHH) immunoglobulin with the CDRs originating from Lama glama (306-434) [Homo sapiens IGHV3-23*04 -(IGHD) -IGHJ4*01, CDR-Kabat [5.17.20] (336-340.355-371.404-423)] fused via peptide linker 435 GGGGA 439 to the 440 CRGDRGDRGDRGDC 453 peptide containing four RGD (human integrin recognition motif repeats (441-452)) arranged as a cyclic polypeptide (C 440 disulfide-bridged to C 453 ), produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV complement factor H modulator
produvofusp [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

PRODUVOFUSP

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