OMECTATUG

UNII:	QZ3WR2DNM3
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	OMECTATUG
GSRS Full Record:	QZ3WR2DNM3 i

2867393-44-8
H-gamma1 heavy chain humanized (1-448) [VH (Homo sapiens IGHV1-8*01 (85.7%) -(IGHD) -IGHJ6*01 (85.7%) G119>D (109), CDR-IMGT [8.8.11] (26-33.51-58.97-107))(1-118) -Homo sapiens IGHG1*01 (100%) G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (215) (119-216), hinge 1-15 (217-231), CH2 (232-341), CH3 D12 (357), L14 (359) (342-446), CHS (447-448)) (119-448)], (221-220')-disulfide with L-kappa light chain humanized (1'-220') [V-KAPPA (Homo sapiens IGKV4-1*01 (88.1%) -IGKJ2*01 (91.7%) I126>R (112), CDR-IMGT [12.3.9] (27'-38'.56'-58'.95'-103')) (1'-113') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (159'), V101 (197')) (114'-220')]; dimer (227-227'':230-230'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, derived from the cell line CHO-K1, lacking the glutamine synthetase (GS-KO) gene and alpha-(1,6)-fucosyltransferase (FUT8-KO) gene, glycoform alfa
Immunoglobulin G1, anti-(human claudin CLDN18.2) (human-Mus musculus monoclonal ASKB589 γ1-chain), disulfide with human-Mus musculus monoclonal ASKB589 κ-chain, dimer
Omectatug
immunoglobulin G1-kappa, anti-[Homo sapiens CLDN18 (claudin 18, claudin-18, surfactant associated protein J, SFTPJ) isoform 2], humanized monoclonal antibody (Omectatug)
omectatug [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

OMECTATUG

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