TARCOCIMAB

UNII:	QNU3MX7NBY
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	TARCOCIMAB
GSRS Full Record:	QNU3MX7NBY i

2408661-40-3
Immunoglobulin G1 [240-alanine,241-alanine,243-alanine,449-cysteine], anti-(human vascular endothelial growth factor A) (human-Mus musculus monoclonal OG1950 γ1-chain), disulfide with human-Mus musculus monoclonal OG1950 κ-chain,(232→232'),(235→235')-bis(disulfide) with immunoglobulin G1 anti-(human vascular endothelial growth factor A) (human-Mus musculus monoclonal OG1950 γ1-chain)disulfide with human-Mus musculus monoclonal OG1950 κ-chain
Immunoglobulin G1-kappa, anti-[Homo sapiens VEGFA (vascular endothelial growth factor A, VEGF-A, VEGF)], humanized monoclonal antibody; gamma1 heavy chain humanized (1-453) [VH (Homo sapiens IGHV3- 30*02 (75.8%) -(IGHD) -IGHJ4*01 (93.3%), CDR-IMGT [8.8.16] (26- 33.51-58.97-112)) (1-123) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1, G1v14 CH2 A1.3, A1.2 (CH1 R120>K (220) (124-221), hinge 1-15 (222-236), CH2 L13.>A (240), L1.2>A (241), G1>A (243) (237- 346), CH3 E12 (362), M14 (364), L123>C (449) (347-451), CHS (452- 453)) (124-453)], (226-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-16*01 (87.4%) -IGKJ1*01 (100%), CDR-IMGT [6.3.9] (27- 32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (232-232'':235-235'')-bisdisulfide, produced in Chinese hamster ovary (CHO)-K1SV cell line lacking the glutamine synthetase gene (GS-KO), glycoform alfa
OG-1950
OG1950
TARCOCIMAB [USAN]
Tarcocimab
tarcocimab [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

TARCOCIMAB

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