BALONCIBART

UNII:	QCD6UJ8KWM
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	BALONCIBART
GSRS Full Record:	QCD6UJ8KWM i

2988795-75-9
Baloncibart
Immunoglobulin G4 [228-proline], anti-(human natriuretic peptide receptor A) (human monoclonal REGN7544 γ4-chain), disulfide with human monoclonal REGN7544 κ-chain, dimer
REGN-7544
REGN7544
baloncibart [INN]
immunoglobulin G4-kappa, anti-[Homo sapiens NPR1 (natriuretic peptide receptor 1, natriuretic peptide receptor A, NPRA, atrionatriuretic peptide receptor A, ANPRA, guanylate cyclase A, GUCY2A)], Homo sapiens monoclonal antibody (H-gamma4 heavy chain Homo sapiens (1-447) [VH (Homo sapiens IGHV3-23*04 (89.6%) -(IGHD) -IGHJ4*01 (100%), CDRIMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, 12-G4v5 h P10 (CH1 (121-218), hinge 1-12 S10>P (228) (219-230), CH2 L92 (309) (231-340), CH3 (341-445), CHS (446-447)) (121-447)], (134-214')-disulfide with L-kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-6*01 (93.7%) -IGKJ3*01 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-07') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (226-226'':229-229'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa)

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UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

BALONCIBART

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