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TUNLUCABTAGENE AUTOLEUCEL

UNII:PH4BB8SRL8
Type:INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:TUNLUCABTAGENE AUTOLEUCEL
GSRS Full Record:

  • BMS-986453
  • BMS-986453 is an investigational drug product containing cryopreserved CD3+CAR+ T cells that have been transduced with a third-generation, replication-incompetent, self-inactivating (SIN) lentiviral vector to express a dual targeting BCMA-specific and GPRC5D-specific chimeric antigen receptor (CAR) for intravenous administration. The dual targeting CAR consists of human anti-BCMA and anti-GPRC5D scFv binding domains, a modified human IgG4 hinge, a CD28 transmembrane anchor, and the 4-1BB and CD3ζ chain signaling domains
  • TUNLUCABTAGENE AUTOLEUCEL [USAN]
  • Tunlucabtagene Autoleucel
  • tunlucabtagene autoleucel [INN]



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