CEVOSTAMAB

UNII:	P86BHN01VE
Formula:
Preferred Substance Name:	CEVOSTAMAB

2249888-53-5
ANTI-FCRH5/CD3 BITE ANTIBODY BFCR4350A
BFCR4350A
BFCR-4350A
BFCR4350A (ANTI-FCRH5/CD3 T-CELL DEPENDENT BISPECIFIC ANTIBODY)
CEVOSTAMAB [INN]
CEVOSTAMAB [USAN]
CEVOSTAMAB [WHO-DD]
FCRH5/CD3 T CELL DEPENDENT BISPECIFIC ANTIBODY BFCR4350A
IMMUNOGLOBULIN G1 (300-GLYCINE,369-TRYPTOPHAN), ANTI-(HUMAN FC RECEPTOR-LIKE PROTEIN FCRL5) (HUMAN-MUS MUSCULUS MONOCLONAL KFCR8534A .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL KFCR8534A .KAPPA.-CHAIN, DIMER WITH IMMUNOGLOBULIN G1 (299-GLYCINE,368-SERINE,370-ALANINE,409-VALINE), ANTI-(HUMAN CD3 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL HCDT4425A .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL HCDT4425A .KAPPA.-CHAIN
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS FC RECEPTOR-LIKE PROTEIN 5, FCRL5 (BXMAS1, FC RECEPTOR HOMOLOG 5, IMMUNE RECEPTOR TRANSLOCATION-ASSOCIATED PROTEIN 2, CD307E-ANTIGEN)) AND ANTI-(HOMO SAPIENS T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN, CD3E (LEU-4 EPSILON CHAIN, CD3E-ANTIGEN)), MONOCLONAL ANTIBODY, BISPECIFIC TETRAVALENT;.GAMMA.1 HEAVY CHAIN ANTI FCRL5 (1-450) (VH (MUS MUSCULUS IGHV2-4*01 (77%) (IGHD)-IGHJ3*01 (91%)/HOMO SAPIENS IGHV4-4*08 (73%) (IGHD)-IGHJ5*01 (86%)) (8.7.14) (1-120)-HOMO SAPIENS IGHG1*03 (CH1(R97>K(217)), CH2(N67>G(300)), CH3(T26>W(369))) (121-450) (223-214')-DISULFIDE WITH .KAPPA. LIGHT CHAIN ANTI FCRL5 (1'-214') (V-KAPPA (HOMO SAPIENS IGKV1-39*01 (83%) IGKJ2*01 (92%))(6.3.9) (1'-107')-HOMO SAPIENS IGKC*01 (108'-214')), (229-228'':232-231'')-BISDISULFIDE WITH .GAMMA.1 HEAVY CHAIN ANTI CD3 (1''-449'') (VH (HOMO SAPIENS IGHV1-3*01 (83%) (IGHD)-IGHJ4*01)) (8.8.12) (1''-119'')-HOMO SAPIENS IGHG1*03 (CH1(R97>K(216'')), CH2(N67>G(299'')), CH3(T26>S(368''), L28>A(370''), Y67>W(409''),)) (120''-449'') (222''-219''')-DISULFIDE WITH .KAPPA. LIGHT CHAIN ANTI CD3 (1'''-219''') (V-KAPPA (HOMO SAPIENS IGKV4-1*01 (89%) IGKJ1*01)) (12.3.8) (1'''-112''')-HOMO SAPIENS IGKC*01 (113'''-219''')); PRODUCED IN CHO CELLS
RECOMBINANT ANTI-FCRH5 X ANTI-CD3 BI-SPECIFIC T-CELL ENGAGER BFCR4350A
RO7187797
RO-7187797

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

CEVOSTAMAB

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