TIMCEVIBART

UNII:	P45RTW33K4
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	TIMCEVIBART
GSRS Full Record:	P45RTW33K4 i

2857862-27-0
Immunoglobulin G1 [232-proline,233-valine,234-alanine,263-glycine,325-glutamine,328-serine], anti-(severe acute respiratory syndrome coronavirus 2 spike glycoprotein S1 receptor-binding domain) (human monoclonal COR-101 γ1-chain), disulfide with human monoclonal COR-101 κ-chain, dimer
Timcevibart
gamma1 heavy chain Homo sapiens (1-445) [VH (Homo sapiens IGHV3-66*01 (96.9%) -(IGHD) -IGHJ3*02 (100%), CDR-IMGT [8.7.10] (26-33.51-57.96-105)) (1-116) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, CH3 D12, L14, G1v50-79 CH2 delE1.4, P1.3, V1.2, A1.A, G27, Q110, S115 (CH1 K120 (213) (117-214), hinge 1-15 (215-229), CH2 E1.4>del, L1.3>P (232), L1.2>V (233), G1.1>A (234), D27>G (263), A110>Q (325), A115>S (328) (230-338), CH3 D12 (354), L14 (356) (339-443), CHS (444-445)) (117-445)], (219-215')-disulfide with kappa light chain Homo sapiens (1'-215') [V-KAPPA (Homo sapiens IGKV1-9*01 (97.9%) -IGKJ3*01 (100%), CDR-IMGT [6.3.10] (27'-32'.50'-52'.89'-98')) (1'-108') -Homo sapiens IGKC*01 (100%), Km3, A45.1 (154'), V101 (192') (109'-215')]; dimer (225-225'':228-228'')-bisdisulfide,
immunoglobulin G1-kappa, anti-[severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein, receptor binding domain (RBD)], Homo sapiens monoclonal antibody
timcevibart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

TIMCEVIBART

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