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TULISOKIBART

UNII:ON09TCS5H3
Type:INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:TULISOKIBART
GSRS Full Record:
ON09TCS5H3
i

  • 2648504-55-4
  • Immunoglobulin G1 [234-alanine,235-alanine,329-alanine], anti-(human tumor necrosis factor superfamily protein TNFSF15) (human monoclonal PRA023 γ1-chain), disulfide with human monoclonal PRA023 κ-chain, dimer
  • PRA-023
  • PRA023
  • TULISOKIBART [USAN]
  • Tulisokibart
  • Tulisokibart [WHO-DD]
  • immunoglobulin G1-kappa, anti-[Homo sapiensTNFSF15 (tumor necrosis factor (TNF) superfamily member 15, TL1A, vascular endothelial cell growth inhibitor 192-A, VEGI192A), membrane and soluble], humanized monoclonal antibody; gamma1 heavy chain humanized (1-446) [VH (Homo sapiens IGHV1-46*02 (80.6%) -(IGHD) -IGHJ6*01 (100%), CDR-IMGT [8.8.9](26-33.51-58.97-105)) (1-116) -Homo sapiens IGHG1*01, G1m17,1, G1v14 CH2 A1.3, A1.2, G1v4 CH2 A114 (CH1 K120 (213) (117-214), hinge 1-15 (215-229), CH2L1.3>A (233), L1.2>A (234), P114>A(328) (230-339), CH3 D12 (355), L14 (357) (340-444), CHS (445-446)) (117-446)], (219-213')- disulfide with kappa light chain humanized (1'-213') [V-KAPPA (Homo sapiens IGKV3D-11*02 (85.6%) -IGKJ4*01 (90.9%), CDR-IMGT [5.3.9] (27-31.49-51.88-96)) (1'-106') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (152), V101 (190) (107'- 213')]; dimer (225-225'': 228-228'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44, glycoform alfa
  • immunoglobulin G1-kappa, anti-[Homo sapiensTNFSF15(tumor necrosis factor (TNF) superfamily member 15, TL1A, vascular endothelial cell growth inhibitor 192-A, VEGI192A), membrane and soluble], humanized monoclonal antibody
  • tulisokibart [INN]




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