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ROZIBAFUSP ALFA

UNII:O9YF5SN7KL
Type:INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:ROZIBAFUSP ALFA
GSRS Full Record:
O9YF5SN7KL
i

  • 2143449-47-0
  • AMG-570
  • ANTI-B7RP-1MAB/BAFF
  • IMMUNOGLOBULIN G2-KAPPA, ANTI-(HUMAN INDUCIBLE COSTIMULATOR (ICOS) LIGAND PROTEIN) HUMAN MONOCLONAL ANTIBODY, FUSED WITH TWO COPIES OF A TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13B (TNFSF13B, B-CELL ACTIVATING FACTOR, BAFF)-BINDING PEPTIDE, GLYCOFORM ALFA
  • IMMUNOGLOBULIN G2-KAPPA, ANTI-(HUMAN INDUCIBLE COSTIMULATOR (ICOS) LIGAND PROTEIN) HUMAN MONOCLONAL ANTIBODY, FUSED WITH TWO COPIES OF A TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13B (TNFSF13B, B-CELL ACTIVATING FACTOR, BAFF)-BINDING PEPTIDE, GLYCOFORM ALFA: .GAMMA.2 HEAVY CHAIN (HOMO SAPIENS VH (HOMO SAPIENS IGHV3-7*01 (98%)-(IGHD)-IGHJ1*01) (8.8.14) (CDRKABATH1: SYWMS (31-35); CDRKABATH2: YIKQDGNEKYYVDSVKG (50-66); CDRKABATH3: EGILWFGDLPTF (99-110)) (1-121)-HOMO SAPIENS IGHG2*01 (CH1 (122-219), HINGE (220-231), CH2 (232-340), CH3 (341-445), CHS (446-447))) (1-447) FUSED BY A G5 LINKER (448-452) AND A (GS)2ATG(GS)2VASS(GS)2ATHL LINKER (471-493) WITH TWO COPIES OF A SYNTHETIC HUMAN TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13B (TNFSF13B, B CELL-ACTIVATING FACTOR, BAFF)-BINDING PEPTIDE (453-470, 494-511), (135-214')-DISULFIDE WITH .KAPPA. LIGHT CHAIN (V-KAPPA (HOMO SAPIENS IGKV1D-16*01 (98%)-IGKJ1*01) (6.3.9) (CDRKABATL1: RASQGISNWLA (24-34); CDRKABATL2: AASSLQS (50-56); CDRKABATL3: QQYDSYPRT (89-97)) (1'-107')-HOMO SAPIENS IGKC*01 (108'-214')) (1'-214'), (223-223'',224-224'',227-227'',230-230'')-TETRAKISDISULFIDE DIMER
  • MEDI-0700
  • ROZIBAFUSP ALFA [USAN]
  • Rozibafusp alfa [WHO-DD]
  • rozibafusp alfa [INN]




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