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DAZUPEGLEUKIN

UNII:NZK8P6D8NH
Type:INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:DAZUPEGLEUKIN
GSRS Full Record:

  • 3049254-88-5
  • Dazupegleukin
  • Interleukin 2 [de-1-alanine,18-arginine,22-glutamic acid,126-lysine] (human), 1-[1-[3-[[(2,3-dihydroxypropoxy)carbonyl]amino]propyl]-L-proline], 1,1-diether with α-hydro-ω-methoxypoly(oxy-1,2-ethanediyl)
  • dazupegleukin [INN]
  • human interleukin 2 (IL2, IL-2, Uniprot: P60568) fragment (2-133, 1-132 in the current sequence) variant (L<sup>17</sup>>R, Q<sup>21</sup> >E, Q<sup>125</sup>>K) modified at the α-amine group of the N-terminal proline with a 3-[({(2RS)-2,3-bis[ω-methoxypoly(oxyethylene)-α-yl]propoxy}carbonyl)amino]propyl group, produced in Escherichia coli strain K12, not glycosylated



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