RADEMIKIBART

UNII:	NWV8DWU7QM
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	RADEMIKIBART
GSRS Full Record:	NWV8DWU7QM i

2648260-80-2
Immunoglobulin G4 [223-proline,de-C-terminal-lysine], anti-(human interleukin 4 receptor subunit α) (human monoclonal CBP-201 γ4-chain), disulfide with human monoclonal CBP-201 κ-chain, dimer
Rademikibart
Rademikibart [WHO-DD]
immunoglobulin G4-kappa, anti-[Homo sapiens IL4R (interleukin 4 receptor, IL4RA, IL-4RA, interleukin 13 receptor, CD124)], Homo sapiens monoclonal antibody (gamma4 heavy chain Homo sapiens (1-441) [VH (Homo sapiens IGHV3-23*04 (88.8%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.7.9] (26-33.51-57.96-104)) (1-115)-Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1 (116-213), hinge 1-12 S10>P (223) (214-225), CH2 L92 (304) (226-335), CH3 (336-440), CHS K2>del (441)) (116-441)], (129-216')-disulfide with kappa light chain Homo sapiens (1'-216') [V-KAPPA (Homo sapiens IGKV3-20*01 (97.9%) -IGKJ1*01 (100%), CDR-IMGT [7.3.10] (27-33.51-53.90-99)) (1'-109') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (155), V101 (193) (110'- 216')]; dimer (221-221'':224-224'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa anti-inflammatory)
rademikibart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

RADEMIKIBART

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