PIVODISGENE PARVEC

UNII:	NVQ25YNH8P
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	PIVODISGENE PARVEC
GSRS Full Record:	NVQ25YNH8P i

2648631-52-9
PIVODISGENE PARVEC [USAN]
Pivodisgene Parvec
RGX-202 (AAV8.Spc5-12.Microdystrophin)
Recombinant replication-defective adeno-associated virus 8 vector RGX-202 synthetic promoter Spc5-12 plus human codon-optimized microdystrophin variant ABD1-H1-R1-R2-R3-H3-R24-H4-CR-CT194 plus synthetic polyadenylation signal plus adeno-associated virus 2 inverted terminal repeat flanks-specifying
pivodisgene parvec [INN]
recombinant, non-replicating adeno-associated virus serotype 8 (rAAV8) vector, encoding a codon-optimised miniaturised version of human dystrophin (microdystrophin variant ABD1-H1-R1-R2-R3-H3-R24-H4-CR-CT194), under control of a synthetic muscle-specific promoter (SPc5-12) and a small synthetic polyadenylation signal; flanked by AAV2 inverted terminal repeats. The expressed microdystrophin variant contains the actin-binding domain 1 (ABD1), four rod domains (R1-3, R24), three hinge domains (H1, H3, H4) and a cysteine rich (CR) domain; it also features the proximal portion of the C-terminal domain, amino acids 3361-3554 (CT194)

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

PIVODISGENE PARVEC

Synonyms and Mappings

Resources