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VARSETATUG

UNII:NPE2WM3V8G
Type:INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:VARSETATUG
GSRS Full Record:
NPE2WM3V8G
i

  • 3036004-28-8
  • H-gamma1 heavy chain humanized (1-445) [VH (Homo sapiens IGHV1-3*01 (81.6%) -(IGHD) -IGHJ6*01 (90.9%) T123>L (111), CDR-IMGT [8.8.9] (26-33.51-58.97-105)) (1-116) -Homo sapiens IGHG1*01 (100%) G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (213) (117-214), hinge 1-15 (215-229), CH2 (230-339), CH3 D12 (355), L14 (357) (340-444), CHS K2>del (445)) (117-445)], (219-265')-disulfide with L-kappa light chain humanized fused at its N-terminal end to a cleavable prodomain (1'-265') [prodomain (1'-46') -Homo sapiens V-KAPPA (Homo sapiens IGKV2D-29*02 (86.0%) -IGKJ2*01 (100%), CDR-IMGT [11.3.9] (73'-83'.101'-103'.140'-148')) (47'-158') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (204'), V101 (242')) (159'-265')]; dimer (225-225'':228-228'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44, glycoform alfa
  • Immunoglobulin G1 [de-446-lysine], anti-(human epithelial cell adhesion molecule) (human monoclonal CX-231 γ1-chain), disulfide with prodomain peptide (synthetic masking moiety and protease-cleavable moiety) fusion protein with human monoclonal CX-231 κ-chain, dimer
  • Varsetatug
  • immunoglobulin G1-kappa, anti-[Homo sapiens EPCAM (epithelial cell adhesion molecule, tumor-associated calcium signal transducer 1, TACSTD1, gastrointestinal tumor-associated protein 2, GA733-2, epithelial glycoprotein 2, EGP-2, KSA, KS1/4 antigen, M4S1, tumor antigen 17-1A, Ep-CAM, EpCAM, CD326)], humanized monoclonal antibody with a cleavable prodomain of 46 amino acids fused at the N-terminal end of the L-kappa light chains (varsetatug)
  • varsetatug [INN]




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