TICALICIBART

UNII:	N8BN99S4JQ
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	TICALICIBART
GSRS Full Record:	N8BN99S4JQ i

3033317-31-3
H-gamma4 heavy chain Homo sapiens (1-441) [VH (Homo sapiens IGHV3-30-5*03 (96.9%) -(IGHD) -IGHJ1*01 (100%), CDR-IMGT [8.8.7] (26-33.51-58.97-103)) (1-114) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, 12-G4v5 h P10(CH1 (115-212), hinge 1-12 S10>P (222) (213-224), CH2 L92 (303) (225-334), CH3 (335-439), CHS (440-441)) (115-441)],(128-220')-disulfide with L-kappa light chain Homo sapiens (1'-220') [V-KAPPA (Homo sapiens IGKV4-1*01 (98.0%) -IGKJ1*01 (100%), CDR-IMGT [12.3.9] (27'-38'.56'-58'.95'-103')) (1'-113') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (159'), V101 (197')) (114'-220')]; dimer (220-220'':223-223'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa
Immunoglobulin G4 [222-proline], anti-(human proprotein convertase subtilisin/kexin type 9) (human monoclonal JK03 γ4-chain), disulfide with human monoclonal JK03 κ-chain, dimer
Ticalicibart
immunoglobulin G4-kappa, anti-[Homo sapiens PCSK9 (proprotein convertase subtilisin/kexin type 9)], Homo sapiens monoclonal antibody (ticalicibart)
ticalicibart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

TICALICIBART

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