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MIVELSIRAN SODIUM

UNII:N85Z572APC
Type:INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:MIVELSIRAN SODIUM
GSRS Full Record:
N85Z572APC
i

  • 2758899-97-5
  • ALN-APP SODIUM
  • MIVELSIRAN SODIUM [USAN]
  • Mivelsiran Sodium
  • RNA, ((5′,6′-dideoxy-6′-phosphono-β-D-ribo-hex-5-enofurano)Um-sp-(2′-deoxy-2′-fluoro)U-sp-Am-Gm-Gm-Um-(3′→3′)-[1-de-β-D-ribofuranosyl-1-[(2S)-2,3-dihydroxypropyl]]m5U-(2′→5′)-Gm-Gm-Am-Um-dT-Um-(2′-deoxy-2′-fluoro)U-Cm-dG-Um-Am-Gm-Cm-Cm-sp-Gm-sp-Um), complex with RNA (Gm-sp-Gm-sp-Cm-Um-Am-(2′-O-hexadecyl)C-Gm-Am-dA-Am-dA-Um-Cm-Cm-Am-Am-Cm-Cm-Um-sp-Am-sp-Am) sodium salt (1:24:1:20)
  • all-P-ambo-2'-O-methyl-P-thioguanylyl-(3'→5')-2'-O-methyl-Pthioguanylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-hexadecylcytidylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-deoxyadenylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-deoxyadenylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methyl-P-thiouridylyl-(3'→5')-2'-O-methyl-P-thioadenylyl-(3'→5')-2'-O-methyladenosine duplex with all-P-ambo-2'-O-methyl-P-thiouridylyl-(5'→3')-2'-O-methyl-P-thioguanylyl-(5'→3')-2'-O-methylcytidylyl-(5'→3')-2'-O-methylcytidylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-O-methyluridylyl-(5'→3')-2'-deoxyguanylyl-(5'→3')-2'-O-methylcytidylyl-(5'→3')-2'-deoxy-2'-fluorouridylyl-(5'→3')-2'-O-methyluridylyl-(5'→3')-thymidylyl-(5'→3')-2'-O-methyluridylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-O-methylguanylyl-(5'→2')-1-de-β-D-ribofuranosyl-1-[(2S)-2,3-dihydroxypropyl]-5-methyluridylyl-(3'→3')-2'-O-methyluridylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-O-methyl-P-thioadenylyl-(5'→3')-2'-deoxy-2'-fluoro-P-thiouridylyl5'→4')-1-de-β-D-ribofuranosyl-1-{(2R,3R,4R,5R)-5-[(1E)-2-phosphonoethen-1-yl]-4-hydroxy-3-methoxyoxolan-2-yl}uridine, sodium salt (1:24: 1:20)




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