ROCONKIBART

UNII:	MD885NVL3Q
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	ROCONKIBART
GSRS Full Record:	MD885NVL3Q i

2638480-59-6
Immunoglobulin G4 [225-proline], anti-(human interleukin 17A) (human-Mus musculus monoclonal JS005 γ4-chain), disulfide with human-Mus musculus monoclonal JS005 κ-chain, dimer
Immunoglobulin G4-kappa, anti-[Homo sapiens IL17A (interleukin 17A, IL-17A)], monoclonal antibody
JS-005
JS005
Roconkibart
gamma4 heavy chain (1-444) [VH (Homo sapiens IGHV1-2*02(85.6%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.10] (26-33.51-58.97-106)) (1-117)-Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1 (118-215), hinge 1-12 S10>P (225) (216-227),CH2 L92 (306) (228-337), CH3 (338-442), CHS (443-444)) (118-444)], (131-219')-disulfide with kappa light chain (1'-219') [V-KAPPA Musmus/Homsap (Mus musculus IGKV1-110*01 (92.0%) - IGKJ2*03 (91.7%) S120>Q (105)/Homo sapiens IGKV2-30*02(88.0%) -IGKJ2*01 (100%), CDR-IMGT [11.3.9] (27-37.55-57.94-102)) (1'-112') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (158), V101 (196) (113'-219')], dimer (223-223'':226-226'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells
roconkibart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

ROCONKIBART

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