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ONVUZOSIRAN

UNII:MC7ZD4X9KB
Type:INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:ONVUZOSIRAN
GSRS Full Record:
MC7ZD4X9KB
i

  • 2982817-49-0
  • ADX-001 free acid
  • ADX-324 free acid
  • ADX001 free acid
  • ADX324 free acid
  • O-[(2R,3S)-2-(hydroxymethyl)oxolan-3-yl] hydrogen all-P-ambo-3'-O-(2-{[(1-{17-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]-3,6,9,12,15-pentaoxaheptadecan-1-yl}-1H-1,2,3-triazol-4-yl)methyl]amino}-2-oxoethyl)-2'-O-(2-{bis[(1-{17-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]-3,6,9,12,15-pentaoxaheptadecan-1-yl}-1H-1,2,3-triazol-4-yl)methyl]amino}-2-oxoethyl)-P-thiocytidylyl-(5'→5')-2'-O-methyl-P-thiouridylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-Omethylguanylyl-( 3'→5')-2'-O-methylguanylyl-(3'→5')-2'-deoxy-2'-fluorocytidylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-deoxy-2'-fluorocytidylyl-(3'→5')-2'-deoxy-2'-fluorocytidylyl-(3'→5')-2'-deoxy-2'-fluorouridylyl-(3'→5')-2'-deoxy-2'-fluorouridylyl-(3'→5')-2'-Omethyluridylyl-( 3'→5')-2'-O-methylguanylyl-(3'→5')-2'-Omethyladenylyl-( 3'→5')-2'-O-methyladenylyl-(3'→5')-2'-Omethyluridylyl-( 3'→5')-2'-O-methyluridylyl-(3'→5')-2'-Omethyladenylyl-( 3'→5')-2'-O-methyl-P-thiocytidylyl-(3'→5')-2'-Omethyl-P-thio-3'-adenylate duplex with all-P-ambo-2'-O-methyl-P-thiouridylyl-(5'→3')-2'-O-methyl-P-thioguanylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-deoxy-2'-fluoroguanylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-deoxy-2'-fluorouridylyl-(5'→3')-2'-O-methylcytidylyl-(5'→3')-2'-deoxy-2'-fluorocytidylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-deoxy-2'-fluoroadenylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-deoxy-2'-fluoroguanylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-deoxy-2'-fluoroadenylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-deoxy-2'-fluorocytidylyl-(5'→3')-2'-O-methyluridylyl-(5'→3')-2'-deoxy-2'-fluorouridylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-deoxy-2'-fluoroadenylyl-(5'→3')-2'-O-methyl-P-thiouridylyl-(5'→3')-2'-deoxy-2'-fluoro-P-thioguanylyl-(5'→3')-2'-O-methyluridine
  • ONVUZOSIRAN [USAN]
  • Onvuzosiran
  • RD-2423 free acid
  • RD2423 free acid
  • RNA, ([3′-O-[2-[[[1-[17-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-3,6,9,12,15-pentaoxaheptadec-1-yl]-1H-1,2,3-triazol-4-yl]methyl]amino]-2-oxoethyl]-2′-O-[2-[bis[[1-[17-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-3,6,9,12,15-pentaoxaheptadec-1-yl]-1H-1,2,3-triazol-4-yl]methyl]amino]-2-oxoethyl]]C-(5′→5′)-sp-Um-sp-Cm-Cm-Am-Gm-Gm-(2′-deoxy-2′-fluoro)C-Um-(2′-deoxy-2′-fluoro)C-(2′-deoxy-2′-fluoro)C-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)U-Um-Gm-Am-Am-Um-Um-Am-Cm-sp-Am-(3′→3′)-sp-[1′-de(6-amino-9H-purin-9-yl)]A), complex with RNA (Um-sp-(2′-deoxy-2′-fluoro)G-sp-Um-(2′-deoxy-2′-fluoro)A-Am-(2′-deoxy-2′-fluoro)U-Um-(2′-deoxy-2′-fluoro)C-Am-(2′-deoxy-2′-fluoro)A-Am-(2′-deoxy-2′-fluoro)G-Gm-(2′-deoxy-2′-fluoro)A-Gm-(2′-deoxy-2′-fluoro)C-Cm-(2′-deoxy-2′-fluoro)U-Gm-(2′-deoxy-2′-fluoro)G-Am-sp-Gm-sp-Um) (1:1)
  • onvuzosiran [INN]




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