FUTERMESTOTUG

UNII:	LSX3UPC7JY
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	FUTERMESTOTUG
GSRS Full Record:	LSX3UPC7JY i

3014361-57-7
C-17226
C17226
FUTERMESTOTUG [USAN]
Futermestotug
H-gamma1 heavy chain humanized (1-452) [VH (Homo sapiens IGHV3-23*04 (90.8%) -(IGHD) -IGHJ4*01 (80.0%) S128>A (122), CDR-IMGT [8.8.15] (26-33.51-58.97-111)) (1-122) -Homo sapiens IGHG1*03v (100%) G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14 (CH1 R120>K (219) (123-220), hinge 1-15 (221-235), CH2 (236-345), CH3 E12 (361), M14 (363) (346-450), CHS (451-452)) (123-452)], (225-214')-disulfide with Lkappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-9*01 (85.3%) -IGKJ4*01 (90.9%) V124>L (104'), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (231-231'':234-234'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa
Immunoglobulin G1, anti-(human/Macaca mulatta CTLA-4 antigen) (human-Mus musculus monoclonal YH001 γ1-chain), disulfide with human-Mus musculus monoclonal YH001 κ-chain, dimer
RECOMBINANT HUMANIZED ANTI-CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4 (ANTI-CTLA4) IGG1 MONOCLONAL ANTIBODY
YH 001 [WHO-DD]
YH-001
YH001
futermestotug [INN]
immunoglobulin G1-kappa, anti-[Homo sapiens CTLA4 (cytotoxic T-lymphocyte associated protein 4, CTLA-4, CD152)], humanized monoclonal antibody;

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

FUTERMESTOTUG

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