TROSUNILIMAB

UNII:	LNN5K7KB5R
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	TROSUNILIMAB
GSRS Full Record:	LNN5K7KB5R i

2550297-60-2
ABBV 382 [WHO-DD]
ABBV-382
Immunoglobulin G1, anti-(human integrin α4β7) (human-Mus musculus monoclonal PR-1794842 γ1-chain), disulfide with human-Mus musculus monoclonal PR-1794842 κ-chain, dimer
PR-1794842
TROSUNILIMAB [USAN]
Trosunilimab
gamma1 heavy chain (1-442) [VH (Homo sapiens IGHV1-69*11 (80.0%) -(IGHD) -IGHJ3*01 (92.3%) M123>T (107), CDR-IMGT [8.8.5] (26-33.51-58.97-101)) (1-112) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 (CH1 R120>K (209) (113-210), hinge 1-15 (211-225), CH2 (226-335), CH3 E12 (351), M14 (353) (336-440), CHS (441-442)) (113-442)], (215-214')-disulfide with kappa light chain (1'-214') [V-KAPPA Musmus/Homsap (Mus musculus IGKV14-100*01 (85.3%) -IGKJ1*01 (91.7%) L124>V (104)/Homo sapiens IGKV1-33*01 (80.0%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (221-221'':224-224'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
immunoglobulin G1-kappa, anti-[Homo sapiens integrin ITGA4_ITGB7 (integrin alpha4 (CD49d)_beta7, integrin α4β7, lymphocyte Peyer's patch adhesion molecule 1, LPAM-1)]
trosunilimab [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

TROSUNILIMAB

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