RILOGROTUG

UNII:	LI86LS4ZUR
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	RILOGROTUG
GSRS Full Record:	LI86LS4ZUR i

2894138-72-6
AV-380
AV-380 (GDF15 MAB)
Immunoglobulin G1, anti-(human growth differentiation factor 15) (human-Mus musculus monoclonal AV-380 γ1-chain), disulfide with human-Mus musculus monoclonal AV-380 κ-chain, dimer
RILOGROTUG [USAN]
Rilogrotug
immunoglobulin G1-kappa, anti-[Homo sapiens Growth/differentiation factor 15 (GDF15), Macrophage inhibitory cytokine 1 (MIC-1)], humanized monoclonal antibody; gamma1 heavy chain humanized (1-450) [VH (Homo sapiens IGHV1-69*02 (83.7%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG1*03 (100%), G1m3, nG1m1 CH1 R120, CH3 E12, M14 (CH1 R120 (217) (121-218), hinge 1-15 (219-233), CH2 (234-343), CH3 E12 (359), M14 (361) (344-448), CHS (449-450)) (121-450)], (223-214')-disulfide with kappa light chain humanized (1'-214') [V- KAPPA (Homo sapiens IGKV1-27*01 (83.2%) -IGKJ2*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (229-229'':232-232'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

RILOGROTUG

Synonyms and Mappings

Resources