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AUTOGENE CEVUMERAN

UNII:L8HDH9IB06
Formula:
Preferred Substance Name:AUTOGENE CEVUMERAN

  • 2365453-34-3
  • A 5'-CAPPED SINGLE-STRANDED MESSENGER RNA (MRNA) CONSTRUCT FOR THE EXPRESSION OF PATIENT-SPECIFIC TUMOUR NEOANTIGENS COMPRISING A 5'-CAP, A 5'-UNTRANSLATED REGION DERIVED FROM HUMAN ALPHA-GLOBIN MRNA, AN OPTIMISED KOZAK SEQUENCE, SEQUENCES ENCODING A SECRETORY SIGNAL PEPTIDE (SEC 2.0), TRANSMEMBRANE AND CYTOPLASMIC DOMAINS OF A MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) CLASS I MOLECULE (MITD), A 3'-UNTRANSLATED REGION (FI) AND A POLY(A)-TAIL; SEQUENCES ENCODING PATIENT SPECIFIC ANTIGENS ARE INSERTED BETWEEN THE SECRETORY SIGNAL PEPTIDE AND THE TRANSMEMBRANE/CYTOPLASMIC ENCODING DOMAINS
  • AUTOGENE CEVUMERAN [INN]
  • AUTOGENE CEVUMERAN [USAN]
  • AUTOGENE CEVUMERAN [WHO-DD]
  • BNT122
  • BNT-122
  • RG 6180
  • RG-6180
  • RNA (RECOMBINANT 5'-(1,2-(M7GM-(5'->5')-P-(P(R))-SP-P-G))-CAPPED 5'-UTR (HUMAN .ALPHA.-GLOBIN RNA-KOZAK)/SECRETORY SIGNAL PEPTIDE SEC2.0-SPECIFYING/PATIENT-SPECIFIC TUMOR NEOANTIGEN-SPECIFYING INSERTION SITE/MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I TRANSMEMBRANE AND CYTOPLASMIC DOMAINS-SPECIFYING/3'-UTR (AES MRNA-MITOCHONDRIAL 12S RRNA)-CONTAINING POLY(A)-TAILED MESSENGER RO7198457 CONSTANT REGION), INNER SALT
  • RO7198457
  • RO-7198457




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