EFADIRELAXIN ALFA

UNII:	L323JVU4Y3
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	EFADIRELAXIN ALFA
GSRS Full Record:	L323JVU4Y3 i

3061442-66-5
Efadirelaxin Alfa
Immunoglobulin G1 [14-alanine,15-alanine,109-alanine,208-leucine,214-serine] (human γ1-chain hinge-CH2-CH3 fragment) fusion protein with peptide linker (GGS) fusion protein with relaxin B-chain [4-glutamine,25-lysine,de-28-tryptophan,de-29-serine] (human) fusion protein with peptide linker (synthetic 13-amino acid) fusion protein with relaxin A-chain [arginyl,22-glutamine] (human), dimer
efadirelaxin alfa [INN]
human immunoglobulin G1 (IgG1) Fc fragment (h-CH2-CH3-CHS domains) (1-227) [Homo sapiens IGHG1*01 (hinge (1-10), CH2 L14>A, L15>A, P109>A (11-120), CH3 M208>L, N214>S (121-225), CHS (226-227))], fused via peptide linker 228GGS230 to a human relaxin B-chain fragment (Uniprot: P04090) (1-27, 231-257 in the current sequence) variant (M4>Q234, M25>K255, 28WS29>del) fused via peptide linker 258 ASDAAGAEAEAGA 271 to human relaxin A-chain (Uniprot: P04090) (1-24, 272-295 in the current sequence) variant (R22>Q293), dimer (6-6':9-9')-bisdisulfide, produced in Chinese hamster ovary (CHO), cell line CHO-K1, glycoform alfa

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

EFADIRELAXIN ALFA

Synonyms and Mappings

Resources