ABELACIMAB

UNII:	KX1N4TV7UY
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	ABELACIMAB
GSRS Full Record:	KX1N4TV7UY i

2098724-83-3
ABELACIMAB [USAN]
Abelacimab [WHO-DD]
IMMUNOGLOBULIN G1, ANTI-(HUMAN BLOOD-COAGULATION FACTOR XI) (HUMAN MONOCLONAL CLONE NVS250519 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL NVS250519 .LAMBDA.-CHAIN, DIMER
NVP-MAA868
abelacimab [INN]
immunoglobulin G1-lambda, anti-[Homo sapiens F11 (coagulation factor XI, FXI, plasma thromboplastin antecedent, PTA)], Homo sapiens monoclonal antibody; gamma1 heavy chain (1-452) [Homo sapiens VH (IGHV3-23*01 (93.9%) -(IGHD) IGHJ4*01 (100%)) [8.8.15] (1-122) -Homo sapiens IGHG1*03, G1m3, nG1m1 (CH1 R120 (219) (123-220), hinge (221-235), CH2 D27>A (270), P114>A (334) (236-345), CH3 E12 (361), M14 (363) (346-450), CHS (451-452)) (123-452)], (225-215')disulfide with lambda light chain (1'-216') [Homo sapiens V-LAMBDA (IGLV1-44*01 (93.5%) -IGLJ2*01 (100%)) [8.3.11] (1'-110') -Homo sapiens IGLC2*01 (111'-216')]; dimer (231-231'':234-234'')-bisdisulfide

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

ABELACIMAB

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