VAMIKIBART

UNII:	KP04MH1JTT
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	VAMIKIBART
GSRS Full Record:	KP04MH1JTT i

2744320-12-3
EBI-031
EBI031
Immunoglobulin G2 [311-alanine], anti-(human interleukin 6) (human monoclonal RG6179 γ2-chain), disulfide with human monoclonal RG6179 κ-chain, dimer
RECOMBINANT HUMANISED IGG2 KAPPA ANTI-INTERLEUKIN 6 MONOCLONAL ANTIBODY RO7200220
RG-6179
RG6179
RO-7200220
RO7200220
VAMIKIBART [USAN]
Vamikibart
Vamikibart [WHO-DD]
immunoglobulin G2-kappa, anti-[Homo sapiens IL6 (interleukin 6)], humanized and chimeric monoclonal antibody; gamma2 heavy chain humanized (1-448) [VH ( Homo sapiens IGHV1-69*11 (86.7%) -(IGHD) -IGHJ5*02 (90.9%) L123>T (117), CDR-IMGT [8.8.15] (26-33.51-58.97-111)) (1-122) - Homo sapiens IGHG2*01, G2m.. CH2 V45.1, G2v8 CH2 A93 (CH1 (123-220), hinge 1-12 (221-232), CH2 V45.1 (283), H93>A (311) (233-341), CH3 (342-446), CHS (447-448)) (123-448)], (136-218')-disulfide with kappa light chain chimeric (1'-218') [V-KAPPA Musmus/Homsap (Mus musculus IGKV3- 2*01 (79.8%) -IGKJ2*03 (90.9%) S120>Q (104)/Homo sapiens IGKV4-1*01 (79.2%) -IGKJ2*01 (100%), CDR-IMGT [10.3.9] (27-36.54-56.93-101)) (1'-111') -Homo sapiens IGKC*01, Km3 A45.1 (157), V101 (195) (112'-218')]; dimer (224-224'':225-225'':228-228'':231-231'')-tetrakisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1M, glycoform alfa
vamikibart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

VAMIKIBART

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